High bilateral bony symmetry in dysplastic and nondysplastic knees: A CT-based 3D evaluation

Description: This dataset contains derived 3D morphological symmetry data of the distal femur, patella, and proximal tibia in knee pairs with no, low-grade, and high-grade trochlear dysplasia, and analysis scripts used to derive the 3D morphological symmetry. All CT scans included in this dataset were originally acquired for other indications (clinical practice or other research studies) and were retrospectively included. The purpose of this study was to evaluate bilateral bony symmetry across different severities of trochlear dysplasia and to determine whether dysplastic knees exhibit reduced morphological symmetry compared with nondysplastic knees. Study design: Bilateral CT scans from 187 subjects were analyzed: • 137 with no trochlear dysplasia • 37 with low grade dysplasia (Dejour type A) • 13 with high grade dysplasia (Dejour types B–D) 3D surface models of the distal femur, patella, and proximal tibia were generated from automated and manually refined segmentations. Morphological symmetry was quantified using Euclidean distances between correspondence points (CPs), obtained by aligning the mirrored left-side models and subsequently non-rigidly registering the corresponding right-side models onto these aligned mirrored left-side models. Content of this dataset: This dataset contains summary statistics of CP distances (1st percentile, 25th percentile, median, 75th percentile, 99th percentile) for: • Distal femur • Patella • Proximal tibia These summary statistics are provided per knee pair and per trochlear dysplasia group. Raw CP level distances are not included due to the high number of CP measurements. Additionally included: • Participant characteristics: age and sex Intended Use This dataset provides the exact aggregated numerical values corresponding to the CP distance boxplots. It is intended for readers who wish to examine the quantitative results more closely. Not Included in This Dataset The following items are not part of this data collection: • Analysis scripts (these may be requested from the collection managers). • CT scans The CT data is not available for reuse outside the Radboudumc. Data reuse is only possible through collaboration. In case of interest or questions, researchers may contact the collection managers.